LJ 001

Modify Date: 2024-01-06 19:41:17

LJ 001 Structure
LJ 001 structure
Common Name LJ 001
CAS Number 851305-26-5 Molecular Weight 327.421
Density 1.4±0.1 g/cm3 Boiling Point 477.3±55.0 °C at 760 mmHg
Molecular Formula C17H13NO2S2 Melting Point N/A
MSDS N/A Flash Point 242.5±31.5 °C

 Use of LJ 001


LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion

 Names

Name LJ-001
Synonym More Synonyms

 LJ 001 Biological Activity

Description LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion
References References 1. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. 2. Vigant F, et al. PLoS Pathog. 2013;9(4):e1003297. 3. Balmer BF, et al. J Virol. 2017 Jan 31;91(4). pii: e02181-16. View Related Products by Target Influenza Virus

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 477.3±55.0 °C at 760 mmHg
Molecular Formula C17H13NO2S2
Molecular Weight 327.421
Flash Point 242.5±31.5 °C
Exact Mass 327.038757
LogP 4.14
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.705

 Synonyms

(5Z)-3-Allyl-5-[(5-phenyl-2-furyl)methylene]-2-thioxo-1,3-thiazolidin-4-one
(5Z)-5-[(5-phenylfuran-2-yl)methylidene]-3-(prop-2-en-1-yl)-2-thioxo-1,3-thiazolidin-4-one
8646IPJ1AP
4-Thiazolidinone, 5-[(5-phenyl-2-furanyl)methylene]-3-(2-propen-1-yl)-2-thioxo-, (5Z)-
LJ-001