8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione

Modify Date: 2024-04-03 10:54:42

8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione Structure
8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione structure
Common Name 8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione
CAS Number 851657-60-8 Molecular Weight 585.65
Density N/A Boiling Point N/A
Molecular Formula C32H35N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione


RSV L-protein-IN-4 (Compound C) is a noncompetitive RSV polymerase inhibitor (IC50: 0.88 μM). RSV L-protein-IN-4 shows antiviral activity against RSV strains (EC50: 0.25 μM)[1].

 Names

Name 8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione

  Biological Activity

Description RSV L-protein-IN-4 (Compound C) is a noncompetitive RSV polymerase inhibitor (IC50: 0.88 μM). RSV L-protein-IN-4 shows antiviral activity against RSV strains (EC50: 0.25 μM)[1].
Related Catalog
Target

0.88 μM (RSV polymerase)[1]

References

[1]. Liuzzi M, et al. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J Virol. 2005 Oct;79(20):13105-15.  

 Chemical & Physical Properties

Molecular Formula C32H35N5O6
Molecular Weight 585.65