Eupatorin

Modify Date: 2024-01-02 20:35:11

Eupatorin Structure
Eupatorin structure
Common Name Eupatorin
CAS Number 855-96-9 Molecular Weight 344.315
Density 1.4±0.1 g/cm3 Boiling Point 587.0±50.0 °C at 760 mmHg
Molecular Formula C18H16O7 Melting Point 194-196°C
MSDS Chinese USA Flash Point 216.0±23.6 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of Eupatorin


Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage[1].

 Names

Name 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one
Synonym More Synonyms

 Eupatorin Biological Activity

Description Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage[1].
Related Catalog
References

[1]. Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One. 2014 Nov 12;9(11):e112536.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 587.0±50.0 °C at 760 mmHg
Melting Point 194-196°C
Molecular Formula C18H16O7
Molecular Weight 344.315
Flash Point 216.0±23.6 °C
Exact Mass 344.089600
PSA 98.36000
LogP 2.96
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.627
Storage condition room temp

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Hazard Codes T
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR UN 2811 6.1 / PGIII
HS Code 2932999099

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles10

More Articles
Analysis of vervain flavonoids by HPLC/Diode array detector method. Its application to quality control.

J. Agric. Food Chem. 47(11) , 4579-82, (1999)

A reversed-phase HPLC procedure is proposed for the determination of seven flavonoids (luteolin, nepetin, hispidulin, jaceosidin, cirsimaritin, cirsilineol, and eupatorin) in vervain samples. A simple...

Flavones and rosmarinic acid from Salvia limbata.

Nat. Prod. Res. 24(20) , 1902-6, (2010)

The genus Salvia (Lamiaceae) contains more than 50 shrub species in Iran, and Salvia limbata C.A. Meyer grows widely in the north and central parts of the country. Six flavones and rosmarinic acid wer...

Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation.

Planta Med. 78(8) , 779-86, (2012)

Cytokines and other inflammatory mediators, such as prostaglandin E₂ (PGE₂) and nitric oxide (NO) produced by cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), respectively, activat...

 Synonyms

MFCD00016929
4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one
5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4-chromenone
3',5-dihydroxy-4',6,7-trimethoxyflavone
eupatorin
6-methoxyluteolin-4',7-dimethyl ether
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