Zomepirac-d4 sodium salt

Modify Date: 2024-09-02 20:32:26

Zomepirac-d4 sodium salt Structure
Zomepirac-d4 sodium salt structure
Common Name Zomepirac-d4 sodium salt
CAS Number 85577-28-2 Molecular Weight 317.74
Density N/A Boiling Point N/A
Molecular Formula C15H10D4ClNNaO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zomepirac-d4 sodium salt


Zomepirac-d4 sodium salt is the deuterium labeled Zomepirac sodium salt. Zomepirac sodium salt (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac sodium salt is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac sodium salt can cause immune-mediated liver injury[1][2].

 Names

Name Zomepirac-d4 sodium salt

 Zomepirac-d4 sodium salt Biological Activity

Description Zomepirac-d4 sodium salt is the deuterium labeled Zomepirac sodium salt. Zomepirac sodium salt (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac sodium salt is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac sodium salt can cause immune-mediated liver injury[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Min Wang, et al. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol. 2002 Jan;17(1):66-71.

[3]. T P Pruss, et al. Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol. 1980 Apr;20(4):216-22.

 Chemical & Physical Properties

Molecular Formula C15H10D4ClNNaO3
Molecular Weight 317.74
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