PKC-IN-7

Modify Date: 2024-02-24 17:22:07

PKC-IN-7 Structure
PKC-IN-7 structure
Common Name PKC-IN-7
CAS Number 860468-10-6 Molecular Weight 443.931
Density N/A Boiling Point N/A
Molecular Formula C26H22ClN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PKC-IN-7


PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.

 Names

Name PKC-IN-7

 PKC-IN-7 Biological Activity

Description PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
References References 1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786. View Related Products by Target PKC

 Chemical & Physical Properties

Molecular Formula C26H22ClN3O2
Molecular Weight 443.931
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