TP0427736 HCl structure
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Common Name | TP0427736 HCl | ||
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CAS Number | 864374-00-5 | Molecular Weight | 298.39 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 634.7±65.0 °C at 760 mmHg | |
Molecular Formula | C14H10N4S2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 333.8±24.7 °C |
Use of TP0427736 HClTP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells[1]. |
Name | TP0427736 |
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Synonym | More Synonyms |
Description | TP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells[1]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 634.7±65.0 °C at 760 mmHg |
Molecular Formula | C14H10N4S2 |
Molecular Weight | 298.39 |
Flash Point | 333.8±24.7 °C |
Exact Mass | 298.034698 |
LogP | 3.37 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.740 |
Storage condition | Store at -20°C |
Water Solubility | DMSO :≥50mg/mL |
Hazard Codes | N |
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6-[4-(4-Methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]-1,3-benzothiazole |
Benzothiazole, 6-[4-(4-methyl-2-thiazolyl)-1H-imidazol-5-yl]- |