Benzyl-PEG7-amine

Modify Date: 2024-01-09 07:56:51

Benzyl-PEG7-amine Structure
Benzyl-PEG7-amine structure
Common Name Benzyl-PEG7-amine
CAS Number 868594-43-8 Molecular Weight 415.521
Density 1.1±0.1 g/cm3 Boiling Point 502.0±45.0 °C at 760 mmHg
Molecular Formula C21H37NO7 Melting Point N/A
MSDS N/A Flash Point 251.1±22.4 °C

 Use of Benzyl-PEG7-amine


Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Phenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-amine
Synonym More Synonyms

 Benzyl-PEG7-amine Biological Activity

Description Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 502.0±45.0 °C at 760 mmHg
Molecular Formula C21H37NO7
Molecular Weight 415.521
Flash Point 251.1±22.4 °C
Exact Mass 415.256989
LogP -0.75
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.492

 Synonyms

1-Phenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-amine
MFCD29049391
2,5,8,11,14,17,20-Heptaoxadocosan-22-amine, 1-phenyl-
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