N-Methyl pemetrexed

Modify Date: 2024-01-17 10:26:51

N-Methyl pemetrexed Structure
N-Methyl pemetrexed structure
Common Name N-Methyl pemetrexed
CAS Number 869791-42-4 Molecular Weight 441.437
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C21H23N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Methyl pemetrexed


N-Methyl pemetrexed is an impurity of Pemetrexed. Pemetrexed is an antifolate cytotoxic agent that can be used for the research of cancer[1].

 Names

Name N-{4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid
Synonym More Synonyms

 N-Methyl pemetrexed Biological Activity

Description N-Methyl pemetrexed is an impurity of Pemetrexed. Pemetrexed is an antifolate cytotoxic agent that can be used for the research of cancer[1].
Related Catalog
References

[1]. Warner A, et, al. Development of a purity control strategy for pemetrexed disodium and validation of associated analytical methodology. J Pharm Biomed Anal. 2015 Feb;105:46-54.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C21H23N5O6
Molecular Weight 441.437
Exact Mass 441.164825
LogP -1.34
Index of Refraction 1.698

 Synonyms

L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
N-{4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid
Pemetrexed Impurity 2
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