AZD-1092

Modify Date: 2024-04-12 23:21:49

AZD-1092 Structure
AZD-1092 structure
Common Name AZD-1092
CAS Number 871656-65-4 Molecular Weight 450.495
Density N/A Boiling Point N/A
Molecular Formula C24H26N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AZD-1092


AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM; exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats; shows potential for treatment of type 2 diabetes.

 Names

Name AZD-1092

 AZD-1092 Biological Activity

Description AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM; exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats; shows potential for treatment of type 2 diabetes.
References References 1. Coope GJ, et al. Br J Pharmacol. 2006 Oct;149(3):328-35. 2. Michael J. Waring, et al. Med. Chem. Commun., 2011, 2, 775-779 View Related Products by Target Glucokinase

 Chemical & Physical Properties

Molecular Formula C24H26N4O5
Molecular Weight 450.495
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