m-PEG6-Boc

Modify Date: 2024-01-10 10:51:46

m-PEG6-Boc Structure
m-PEG6-Boc structure
Common Name m-PEG6-Boc
CAS Number 874208-90-9 Molecular Weight 424.526
Density 1.0±0.1 g/cm3 Boiling Point 467.7±40.0 °C at 760 mmHg
Molecular Formula C20H40O9 Melting Point N/A
MSDS N/A Flash Point 197.2±27.4 °C

 Use of m-PEG6-Boc


m-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG7-t-butyl ester
Synonym More Synonyms

 m-PEG6-Boc Biological Activity

Description m-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 467.7±40.0 °C at 760 mmHg
Molecular Formula C20H40O9
Molecular Weight 424.526
Flash Point 197.2±27.4 °C
Exact Mass 424.267242
LogP -0.73
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.447

 Synonyms

2-Methyl-2-propanyl 2,5,8,11,14,17,20-heptaoxatricosan-23-oate
MFCD28950751
2,5,8,11,14,17,20-Heptaoxatricosan-23-oic acid, 1,1-dimethylethyl ester
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