GSK894281

Modify Date: 2024-04-06 10:19:34

GSK894281 structure	Common Name	GSK894281
	CAS Number	874958-63-1	Molecular Weight	473.56000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₈FN₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK894281

GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].

Name	N-[5-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl]-3-fluoro-4-(5-methylfuran-2-yl)benzenesulfonamide
Synonym	More Synonyms

Description	GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> GHSR
References	[1]. A D Shafton, et al.Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation. Neurogastroenterol Motil. 2009 Jan;21(1):71-7.

Molecular Formula	C₂₄H₂₈FN₃O₄S
Molecular Weight	473.56000
Exact Mass	473.17800
PSA	92.19000
LogP	5.93770

unii-dhj6673as1

GSK894281

Use of GSK894281

Names

GSK894281 Biological Activity

Chemical & Physical Properties

Synonyms