3-(2'-phenyl-2'-Cyclopentyl-2'-hydroxyethoxy)quinuclidine
Modify Date: 2024-01-01 18:19:40
3-(2'-phenyl-2'-Cyclopentyl-2'-hydroxyethoxy)quinuclidine structure
|
Common Name | 3-(2'-phenyl-2'-Cyclopentyl-2'-hydroxyethoxy)quinuclidine | ||
|---|---|---|---|---|
| CAS Number | 87827-02-9 | Molecular Weight | 315.450 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 461.0±35.0 °C at 760 mmHg | |
| Molecular Formula | C20H29NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 232.6±25.9 °C | |
Use of 3-(2'-phenyl-2'-Cyclopentyl-2'-hydroxyethoxy)quinuclidinePenehyclidine, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1][2]. |
| Name | 2-(1-azabicyclo[2.2.2]octan-3-yloxy)-1-cyclopentyl-1-phenylethanol |
|---|---|
| Synonym | More Synonyms |
| Description | Penehyclidine, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1][2]. |
|---|---|
| Related Catalog | |
| Target |
NF-κB |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 461.0±35.0 °C at 760 mmHg |
| Molecular Formula | C20H29NO2 |
| Molecular Weight | 315.450 |
| Flash Point | 232.6±25.9 °C |
| Exact Mass | 315.219818 |
| PSA | 32.70000 |
| LogP | 3.44 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.588 |
| 2-(1-Azabicyclo[2.2.2]oct-3-yloxy)-1-cyclopentyl-1-phenylethanol |
| Benzenemethanol, α-((1-azabicyclo(2.2.2)oct-3-yloxy)methyl)-α-cyclopentyl- |
| UNII:353CX8CSHD |
| Benzenemethanol, α-[(1-azabicyclo[2.2.2]oct-3-yloxy)methyl]-α-cyclopentyl- |
| m 8218 |
| 3-(2'-phenyl-2'-Cyclopentyl-2'-hydroxyethoxy)quinuclidine |