Metorphamide

Modify Date: 2024-01-03 18:52:45

Metorphamide structure	Common Name	Metorphamide
	CAS Number	88377-68-8	Molecular Weight	984.17900
	Density	1.42g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₄H₆₉N₁₅O₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Metorphamide

Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.

Name	adrenorphin
Synonym	More Synonyms

Description	Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Cancer Peptides
Target	Ki: 12 nM (μ-opioid receptor)[1]
In Vitro	Adrenorphin (Metorphamide) is a opioid octapeptide from bovine brain, acts as a potent agonist of μ-opioid receptor, with Ki of 12 nM. The binding ratios of Ki for μ-opioid receptor/Ki for δ-opioid receptor of 0.04 and of Ki for μ-opioid receptor/Ki for κ-opioid receptor of 0.46[1]. Adrenorphin potently inhibits catecholamine secretion evoked by 10 μM nicotine in cultured human pheochromocytoma 6 cells, with an IC50 of 1.1 μM[2].
References	[1]. Weber E, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80(23):7362-6. [2]. Yanase T, et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64(4):692-7.

Density	1.42g/cm3
Molecular Formula	C₄₄H₆₉N₁₅O₉S
Molecular Weight	984.17900
Exact Mass	983.51200
PSA	442.14000
LogP	3.10080
Index of Refraction	1.656
Storage condition	2-8℃

WGK Germany	3

H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2

METORPHINAMIDE

METORPHAMIDE

PROENKEPHALIN (206-213) (BOVINE)

adrenorphin amide

TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2

METORPHIN

tyr-gly-gly-phe-met-arg-arg-val amide

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2
Price: Click To Check
Purity: 98.0%
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GL Biochem (Shanghai) Ltd.
China
Product Name: Metorphamide
Price: $Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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Price: ￥770/1 mg

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