MLS1082

Modify Date: 2024-02-03 19:44:56

MLS1082 Structure
MLS1082 structure
Common Name MLS1082
CAS Number 883958-36-9 Molecular Weight 385.458
Density 1.3±0.1 g/cm3 Boiling Point 520.1±60.0 °C at 760 mmHg
Molecular Formula C24H23N3O2 Melting Point N/A
MSDS N/A Flash Point 268.4±32.9 °C

 Use of MLS1082


MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.

 Names

Name 2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione
Synonym More Synonyms

 MLS1082 Biological Activity

Description MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.
References References 1. Luderman KD, et al. Mol Pharmacol. 2018 Aug 1. pii: mol.118.113175. View Related Products by Target Dopamine Receptor

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 520.1±60.0 °C at 760 mmHg
Molecular Formula C24H23N3O2
Molecular Weight 385.458
Flash Point 268.4±32.9 °C
Exact Mass 385.179016
LogP 2.78
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.688

 Synonyms

Pyrimido[4,5-b]quinoline-4,5(3H,10H)-dione, 2-cyclohexyl-10-methyl-3-phenyl-
2-Cyclohexyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione
2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione
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