883958-36-9

883958-36-9 structure

Name: MLS1082
Chemical Name: 2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione
CAS Number: 883958-36-9
Molecular Formula: C₂₄H₂₃N₃O₂
Molecular Weight: 385.458
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2020-01-11 23:17:50
Modify Date: 2024-02-03 19:44:56
MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.

Name	2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione
Synonyms	Pyrimido[4,5-b]quinoline-4,5(3H,10H)-dione, 2-cyclohexyl-10-methyl-3-phenyl- 2-Cyclohexyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione 2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione

Description	MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.
References	References 1. Luderman KD, et al. Mol Pharmacol. 2018 Aug 1. pii: mol.118.113175. View Related Products by Target Dopamine Receptor