Boc-amido-PEG9-amine

Modify Date: 2024-04-03 15:39:25

Boc-amido-PEG9-amine Structure
Boc-amido-PEG9-amine structure
Common Name Boc-amido-PEG9-amine
CAS Number 890091-43-7 Molecular Weight 556.68700
Density 1.082g/cm3 Boiling Point 609.8ºC at 760 mmHg
Molecular Formula C25H52N2O11 Melting Point N/A
MSDS USA Flash Point 322.6ºC

 Use of Boc-amido-PEG9-amine


Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonym More Synonyms

 Boc-amido-PEG9-amine Biological Activity

Description Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.082g/cm3
Boiling Point 609.8ºC at 760 mmHg
Molecular Formula C25H52N2O11
Molecular Weight 556.68700
Flash Point 322.6ºC
Exact Mass 556.35700
PSA 150.91000
LogP 1.52390
Index of Refraction 1.465

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
RIDADR NONH for all modes of transport

 Synonyms

O-(2-Aminoethyl)-O inverted exclamation marka-[2-(Boc-amino)ethyl]octaethylene glycol
O-(2-aminoethyl)-O'-[2-(Boc-amino)ethyl]octaethylene glycol
Boc-PEG-amine (n=9)
(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}-ethoxy)ethoxy]ethoxy}ethyl)carbamic acid tert-butyl ester
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