Tazobactam Sodium Salt
Tazobactam Sodium Salt structure
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Common Name | Tazobactam Sodium Salt | ||
|---|---|---|---|---|
| CAS Number | 89785-84-2 | Molecular Weight | 322.27300 | |
| Density | 1.92 g/cm3 | Boiling Point | 707.1ºC at 760 mmHg | |
| Molecular Formula | C10H11N4NaO5S | Melting Point | 140-147ºC | |
| MSDS | Chinese USA | Flash Point | 381.4ºC | |
Use of Tazobactam Sodium SaltTazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp.. |
| Name | tazobactam sodium |
|---|---|
| Synonym | More Synonyms |
| Description | Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp.. |
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| Related Catalog | |
| References |
| Density | 1.92 g/cm3 |
|---|---|
| Boiling Point | 707.1ºC at 760 mmHg |
| Melting Point | 140-147ºC |
| Molecular Formula | C10H11N4NaO5S |
| Molecular Weight | 322.27300 |
| Flash Point | 381.4ºC |
| Exact Mass | 322.03500 |
| PSA | 133.67000 |
| Storage condition | Store at 0-5°C |
| Water Solubility | H2O: 50 mg/mL, clear, colorless |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | XI0191500 |
| HS Code | 2934999090 |
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Tazobactam Sodi... CAS#:89785-84-2 |
| Literature: Journal of Medicinal Chemistry, , vol. 30, # 8 p. 1469 - 1474 |
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Tazobactam Sodi... CAS#:89785-84-2 |
| Literature: EP1759697 A1, ; Page/Page column 2-3 ; |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.
Clin. Chem. Lab Med. 53(5) , 781-91, (2015) Recent studies have demonstrated highly variable blood concentrations of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in critically ill patients with a high incidence of ... |
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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
Nucleic Acids Res. 39 , D1035-41., (2011) DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, ... |
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Variable susceptibility to piperacillin/tazobactam amongst Klebsiella spp. with extended-spectrum beta-lactamases.
J. Antimicrob. Chemother. 51 , 605-612, (2003) MICs of piperacillin/tazobactam are conventionally determined by varying the concentration of piperacillin in the presence of a fixed 4 mg/L tazobactam. When tested in this way, the MIC distribution f... |
| 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)- |
| 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)- |
| Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| (2S,3S,5R)-3-méthyl-7-oxo-3-(1H-1,2,3-triazol-1-ylméthyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate-4,4-dioxyde de sodium |
| Tazobactam Sodium |
| MFCD00917472 |
| Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 4,4-dioxide |
| [2S-(2a,3b,5a)]-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)- (1:1) |
| Tazobactam sodium salt |
| CL 307,579 |