β-D-Mannopyranuronic acid

Modify Date: 2024-01-03 17:50:12

β-D-Mannopyranuronic acid structure	Common Name	β-D-Mannopyranuronic acid
	CAS Number	9005-32-7	Molecular Weight	194.139
	Density	2.0±0.1 g/cm3	Boiling Point	495.2±45.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₂₆O₁₉	Melting Point	300 °C
	MSDS	Chinese USA	Flash Point	211.1±22.2 °C

Use of β-D-Mannopyranuronic acid

Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties[1][2][3].

Name	alginic acid
Synonym	More Synonyms

Description	Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Endocrinology Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
In Vitro	Alginic acid (AA) is a kind of polysaccharide extracted from brown seaweeds and has been widely used in food industry[2].
References	[1]. Guo X, et al. Structures, properties and application of alginic acid: A review. Int J Biol Macromol. 2020;162:618-628. [2]. Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099. [3]. Jeong HJ, et al. Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation. Clin Exp Allergy. 2006;36(6):785-794.

Density	2.0±0.1 g/cm3
Boiling Point	495.2±45.0 °C at 760 mmHg
Melting Point	300 °C
Molecular Formula	C₁₈H₂₆O₁₉
Molecular Weight	194.139
Flash Point	211.1±22.2 °C
Exact Mass	194.042648
PSA	127.45000
LogP	-2.88
Appearance of Characters	Powder \| White to pale yellow to beige
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.685
Water Solubility	H2O: insoluble, but swells \| Insoluble in water.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	24/25-36-26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	AZ5775000

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β-D-Mannopyranuronic acid

MFCD00081309