Protamine sulfates
Modify Date: 2024-01-02 19:51:08
Protamine sulfates structure
|
Common Name | Protamine sulfates | ||
|---|---|---|---|---|
| CAS Number | 9009-65-8 | Molecular Weight | 6691.85629 | |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 330.0±11.0 °C at 760 mmHg | |
| Molecular Formula | C264H460N128O65S7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Protamine sulfatesProtamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer[1][2][3]. |
| Name | Protamine sulfates |
|---|---|
| Synonym | More Synonyms |
| Description | Protamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | Protamine sulfate has an inhibitory effect on thrombin in the conversion of fibrinogen to fibrin, and that this inhibition is concentration dependent, partial, and reversible[3]. Protamine sulfate is a 5-kDa cationic polypeptide derived from salmon sperm that can bind negatively charged unfractionated heparin (UFH). Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation[4]. |
| References |
| Density | 2.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 330.0±11.0 °C at 760 mmHg |
| Molecular Formula | C264H460N128O65S7 |
| Molecular Weight | 6691.85629 |
| Exact Mass | 6687.46695 |
| LogP | -1.03 |
| Appearance of Characters | amorphous powder | white |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.537 |
| Storage condition | +2C to +8C |
| Water Solubility | H2O: 10 mg/mL | It is sparingly soluble in water. |
| Safety Phrases | 22-24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | VO9470000 |
| H2SO4 |
| EINECS 236-903-3 |
| Oil of vitriol |
| MFCD00064589 |
| UNII:0DE9724IHC |
| Sulfate, hydrogen |
| Sulfuric(VI) acid |
| Sulfuric acid |
| Sulphuric acid |