Desmethyl ferroquine

Modify Date: 2024-01-10 17:50:11

Desmethyl ferroquine Structure
Desmethyl ferroquine structure
Common Name Desmethyl ferroquine
CAS Number 903546-18-9 Molecular Weight 411.66
Density N/A Boiling Point N/A
Molecular Formula C22H14ClFeN3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desmethyl ferroquine


Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].

 Names

Name Desmethyl ferroquine

 Desmethyl ferroquine Biological Activity

Description Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].
Related Catalog
In Vitro The estimate of the apparent terminal half-life of Ferroquine is 15.9 days. However, the equally active principal metabolite Desmethyl ferroquine (DMFQ) has a longer t1/2z, with an overall mean estimate of 31.4 days[1].
References

[1]. Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73.

 Chemical & Physical Properties

Molecular Formula C22H14ClFeN3
Molecular Weight 411.66