chymostatin

Modify Date: 2024-01-02 01:54:24

chymostatin structure	Common Name	chymostatin
	CAS Number	9076-44-2	Molecular Weight	607.701
	Density	1.3±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₁H₄₁N₇O₆	Melting Point	276-278℃
	MSDS	Chinese USA	Flash Point	N/A

Use of chymostatin

Chymostatin is a potent cathepsin G inhibitor. Chymostatin inhibits fungal growth when combined with other pepsin inhibitors. Chymostatin can be used for acute lung injury and pancreatitis research[1].

Name	N-[-Nα-carbonyl-capreomycidine-Val-Phe-al]-Phe
Synonym	More Synonyms

Description	Chymostatin is a potent cathepsin G inhibitor. Chymostatin inhibits fungal growth when combined with other pepsin inhibitors. Chymostatin can be used for acute lung injury and pancreatitis research[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
References	[1]. Chen Yang, et al. Protective Effects of Chymostatin on Paraquat-Induced Acute Lung Injury in Mice. Inflammation

Density	1.3±0.1 g/cm3
Melting Point	276-278℃
Molecular Formula	C₃₁H₄₁N₇O₆
Molecular Weight	607.701
Exact Mass	607.311829
PSA	201.61000
LogP	4.00
Index of Refraction	1.640
Storage condition	−20°C
Water Solubility	DMSO: 10 mM Stock solutions stable for months at −20 °C.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	22-24/25-36-26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GC3047700

Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei.

PLoS ONE 10 , e0134723, (2015)

The filamentous fungus Trichoderma reesei has tremendous capability to secrete proteins. Therefore, it would be an excellent host for producing high levels of therapeutic proteins at low cost. Develop...

Estrogen inhibits mast cell chymase release to prevent pressure overload-induced adverse cardiac remodeling.

Hypertension 65(2) , 328-34, (2015)

Estrogen regulation of myocardial chymase and chymase effects on cardiac remodeling are unknown. To test the hypothesis that estrogen prevents pressure overload-induced adverse cardiac remodeling by i...

Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism.

Am. J. Physiol. Heart Circ. Physiol. 305(5) , H644-50, (2013)

Angiotensin-(1-12) [ANG-(1-12)], a new member of the renin-angiotensin system, is recognized as a renin independent precursor for ANG II. However, the processing of ANG-(1-12) in the circulation in vi...

N-{[(1S)-1-[(4S)-2-Amino-1,4,5,6-tetrahydro-4-pyrimidinyl]-2-{[(2S)-4-methyl-1-oxo-1-{[(2S)-1-oxo-3-phenyl-2-propanyl]amino}-2-pentanyl]amino}-2-oxoethyl]carbamoyl}-L-phenylalanine

MFCD00071059

CHYMOSTATIN (MICROBIAL PRODUCT)

Chymostatin

CHYMOSTATIN, 5 MG

L-Phenylalanine, N-[[[(1S)-2-[[(1S)-1-[[[(1S)-1-formyl-2-phenylethyl]amino]carbonyl]-3-methylbutyl]amino]-1-[(4S)-hexahydro-2-imino-4-pyrimidinyl]-2-oxoethyl]amino]carbonyl]-

CHYMOSTATIN (25 MG )

CHYMOSTATIN (ACTINOMYCETES)