anemonin

Modify Date: 2024-01-09 19:12:13

anemonin Structure
anemonin structure
Common Name anemonin
CAS Number 90921-11-2 Molecular Weight 192.17
Density 1.45±0.1 g/cm3 (20 ºC 760 Torr) Boiling Point N/A
Molecular Formula C10H8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of anemonin


(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].

 Names

Name 1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione
Synonym More Synonyms

 anemonin Biological Activity

Description (Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].
Related Catalog
References

[1]. Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17(1):39.  

[2]. Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116(3):518-27.  

 Chemical & Physical Properties

Density 1.45±0.1 g/cm3 (20 ºC 760 Torr)
Molecular Formula C10H8O4
Molecular Weight 192.17
Exact Mass 192.04200
PSA 52.60000
LogP 0.48380

 Safety Information

HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

protoanemonin