AGN 210676
Modify Date: 2024-01-31 19:14:34
AGN 210676 structure
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Common Name | AGN 210676 | ||
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| CAS Number | 910562-15-1 | Molecular Weight | 431.54500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H29NO5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AGN 210676AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. |
| Name | 5-[[(2R)-1-[4-[(1S)-1-hydroxyhexyl]phenyl]-5-oxopyrrolidin-2-yl]methoxymethyl]thiophene-2-carboxylic acid |
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| Synonym | More Synonyms |
| Description | AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. |
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| Related Catalog | |
| Target |
EP2 Receptor:5 nM (EC50) hEP3A Receptor:153 nM (EC50) hDP Receptor:7749 nM (EC50) |
| In Vitro | AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1]. |
| References |
[1]. Old, David W, et al. SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS. US20070203222A1. |
| Molecular Formula | C23H29NO5S |
|---|---|
| Molecular Weight | 431.54500 |
| Exact Mass | 431.17700 |
| PSA | 115.31000 |
| LogP | 4.83720 |
| unii-v0li771s16 |
| simenepag |