4-(3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

Modify Date: 2024-01-26 14:19:27

4-(3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile structure	Common Name	4-(3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
	CAS Number	915086-32-7	Molecular Weight	405.39400
	Density	1.52±0.1 g/cm3 (20 °C, 760 mmHg)	Boiling Point	548.7±60.0 °C (760 mmHg)
	Molecular Formula	C₁₉H₁₄F₃N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4-(3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile

Androgen receptor antagonist 9 (compound 28) is an antagonist of the androgen receptor[1].

Name	Benzonitrile, 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl]-2-(trifluoromethyl)
Synonym	More Synonyms

Description	Androgen receptor antagonist 9 (compound 28) is an antagonist of the androgen receptor[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Jung ME, et al. Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC). J Med Chem. 2010 Apr 8;53(7):2779-96.

4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl]-2-trifluoromethylbenzonitrile

4-[3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl]-2-trifluoromethylbenzonitrile