CAY10575

Modify Date: 2024-01-10 15:55:13

CAY10575 Structure
CAY10575 structure
Common Name CAY10575
CAS Number 916985-21-2 Molecular Weight 487.549
Density 1.5±0.1 g/cm3 Boiling Point 735.4±70.0 °C at 760 mmHg
Molecular Formula C22H21N3O6S2 Melting Point N/A
MSDS N/A Flash Point 398.5±35.7 °C

 Use of CAY10575


IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1].

 Names

Name 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(4-methylsulfonylphenyl)methoxy]thiophene-2-carboxamide
Synonym More Synonyms

 CAY10575 Biological Activity

Description IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1].
Related Catalog
Target

IKK2:0.075 μM (IC50)

References

[1]. Xie HZ, et al. Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. J Biomol Struct Dyn. 2011 Aug;29(1):165-79.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 735.4±70.0 °C at 760 mmHg
Molecular Formula C22H21N3O6S2
Molecular Weight 487.549
Flash Point 398.5±35.7 °C
Exact Mass 487.087189
PSA 159.36000
LogP 1.74
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.671

 Synonyms

5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[4-(methylsulfonyl)benzyl]oxy}-2-thiophenecarboxamide
2-Thiophenecarboxamide, 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[4-(methylsulfonyl)phenyl]methoxy]-
HMS3229L15
5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-{[4-(methylsulfonyl)benzyl]oxy}thiophene-2-carboxamide
benzimidazole-thiophene carboxamide,2