Lorediplon
Modify Date: 2024-01-02 18:23:10
Lorediplon structure
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Common Name | Lorediplon | ||
|---|---|---|---|---|
| CAS Number | 917393-39-6 | Molecular Weight | 394.42200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H15FN4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LorediplonLorediplon is a novel non-benzodiazepine, hypnotic drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep.Target: GABALorediplon is a drug for the treatment of insomnia, has been successfully completed with a best-in-class efficacy profile in terms of maintaining sleep and sleep quality, Lorediplon targets GABAA. [1] Lorediplon demonstrates a minimum of 10-fold and 6-fold increase in potency (respectively) in the spontaneous motor activation studies. At concentrations of 1.2mg/kg, Lorediplon demonstrates a 57%increased effect on Slow Wave Sleep (SWS), when compared with a placebo.[2] |
| Name | N-[2-fluoro-5-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-N-methylacetamide |
|---|---|
| Synonym | More Synonyms |
| Description | Lorediplon is a novel non-benzodiazepine, hypnotic drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep.Target: GABALorediplon is a drug for the treatment of insomnia, has been successfully completed with a best-in-class efficacy profile in terms of maintaining sleep and sleep quality, Lorediplon targets GABAA. [1] Lorediplon demonstrates a minimum of 10-fold and 6-fold increase in potency (respectively) in the spontaneous motor activation studies. At concentrations of 1.2mg/kg, Lorediplon demonstrates a 57%increased effect on Slow Wave Sleep (SWS), when compared with a placebo.[2] |
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| Related Catalog | |
| References |
| Molecular Formula | C20H15FN4O2S |
|---|---|
| Molecular Weight | 394.42200 |
| Exact Mass | 394.09000 |
| PSA | 95.81000 |
| LogP | 3.81060 |
| Lorediplon |
| N-(2-Fluoro-5-(3-(thiophene-2-carbonyl)pyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-methylacetamide |
| Lorediplon [INN] |
| Acetamide,N-(2-fluoro-5-(3-(2-thienylcarbonyl)pyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-methyl |
| UNII-VKU6Z23NSY |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Lorediplon
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Lorediplon
- Price: $300.0/100mg $600.0/250mg $1500.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Lorediplon
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
Get all suppliers and price by the below link:
Price: $106/10mM*1mLinDMSO
Reference only. check more Lorediplon price