CCMI structure
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Common Name | CCMI | ||
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CAS Number | 917837-54-8 | Molecular Weight | 388.24700 | |
Density | 1.412±0.06 g/cm3(Predicted) | Boiling Point | 605.4±55.0 °C | |
Molecular Formula | C19H15Cl2N3O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of CCMICCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1]. |
Name | (Z)-3-(4-chloroanilino)-N-(4-chlorophenyl)-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide |
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Synonym | More Synonyms |
Description | CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1]. |
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Related Catalog | |
Target |
α7 nAChR[1] |
In Vitro | CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs[1]. |
References |
Density | 1.412±0.06 g/cm3(Predicted) |
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Boiling Point | 605.4±55.0 °C |
Molecular Formula | C19H15Cl2N3O2 |
Molecular Weight | 388.24700 |
Exact Mass | 387.05400 |
PSA | 67.16000 |
LogP | 5.52750 |
Hazard Codes | Xn |
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MFCD18086897 |