TTA-P1

Modify Date: 2024-01-09 22:42:05

TTA-P1 Structure
TTA-P1 structure
Common Name TTA-P1
CAS Number 918333-06-9 Molecular Weight 389.33500
Density N/A Boiling Point N/A
Molecular Formula C19H27Cl2FN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TTA-P1


TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy[1].

 Names

Name 3,5-dichloro-N-[[(3S,4R)-1-(3,3-dimethylbutyl)-3-fluoropiperidin-4-yl]methyl]benzamide

 TTA-P1 Biological Activity

Description TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy[1].
Related Catalog
References

[1]. Uebele VN, Nuss CE, Fox SV, et al. Positive allosteric interaction of structurally diverse T-type calcium channel antagonists. Cell Biochem Biophys. 2009;55(2):81-93.

 Chemical & Physical Properties

Molecular Formula C19H27Cl2FN2O
Molecular Weight 389.33500
Exact Mass 388.14800
PSA 35.83000
LogP 5.33210