3-Aminopropyltriethoxysilane

Modify Date: 2024-01-02 15:41:21

3-Aminopropyltriethoxysilane structure	Common Name	3-Aminopropyltriethoxysilane
	CAS Number	919-30-2	Molecular Weight	221.369
	Density	0.9±0.1 g/cm3	Boiling Point	222.1±13.0 °C at 760 mmHg
	Molecular Formula	C₉H₂₃NO₃Si	Melting Point	-70 °C
	MSDS	Chinese USA	Flash Point	104.4±0.0 °C
	Symbol	GHS05, GHS07	Signal Word	Danger

Use of 3-Aminopropyltriethoxysilane

3-Aminopropyltriethoxysilane is a common method for biomolecule immobilization on silicon and silicon derivatives such as silicon nitride (Si3N4)[1].

Name	(3-Aminopropyl)triethoxysilane
Synonym	More Synonyms

Description	3-Aminopropyltriethoxysilane is a common method for biomolecule immobilization on silicon and silicon derivatives such as silicon nitride (Si3N4)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Saengdee P, et al. Optimization of 3-aminopropyltriethoxysilane functionalization on silicon nitride surface for biomolecule immobilization. Talanta. 2020;207:120305.

Density	0.9±0.1 g/cm3
Boiling Point	222.1±13.0 °C at 760 mmHg
Melting Point	-70 °C
Molecular Formula	C₉H₂₃NO₃Si
Molecular Weight	221.369
Flash Point	104.4±0.0 °C
Exact Mass	221.144714
PSA	53.71000
LogP	1.37
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.433
Storage condition	Store at RT.
Stability	Stable. Incompatible with acids, strong oxidizing agents. May decompose on exposure to moisture.
Water Solubility	REACTS

3-Aminopropyltriethoxysilane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX2100000

CHEMICAL NAME :: 1-Propanamine, 3-(triethoxysilyl)-

CAS REGISTRY NUMBER :: 919-30-2

BEILSTEIN REFERENCE NO. :: 1754988

LAST UPDATED :: 199710

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C9-H23-N-O3-Si

MOLECULAR WEIGHT :: 221.42

WISWESSER LINE NOTATION :: Z3-SI-O2&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1233,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/19/1972

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1233,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1780 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Behavioral - excitement Lungs, Thorax, or Respiration - emphysema Blood - changes in leukocyte (WBC) count

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 11,118,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 260 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RCRVAB Russian Chemical Reviws (English Translation). Translation of USKHAB. (Royal Soc. of Chemistry, Distribution Centre, Blackhorse Rd., Letchworth, Herts SG6 1HN, UK) V.29- 1960- Volume(issue)/page/year: 38,975,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/19/1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHABA8 Chemical Abstracts. (Chemical Abstracts Service, Box 3012, Columbus, OH 43210) V.1- 1907- Volume(issue)/page/year: 70,36149,1969 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 147 mg/m3/6H/4W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0526411-2 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1992 No. of Facilities: 210 (estimated) No. of Industries: 6 No. of Occupations: 5 No. of Employees: 874 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1992 No. of Facilities: 1723 (estimated) No. of Industries: 22 No. of Occupations: 34 No. of Employees: 33590 (estimated) No. of Female Employees: 5422 (estimated)

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H314-H317
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive
Risk Phrases	R22;R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 2735 8/PG 2
WGK Germany	1
RTECS	TX2100000
Packaging Group	III
Hazard Class	8
HS Code	29310095

(3-Chloropropyl...

CAS#:5089-70-3

~80%

3-Aminopropyltr...

CAS#:919-30-2

Literature: Dynamit Nobel Aktiengesellschaft Patent: US4234503 A1, 1980 ;

Triethoxysilane

CAS#:998-30-1

Allylamine

CAS#:107-11-9

~0%

beta-aminopropy...

CAS#:53218-21-6

3-Aminopropyltr...

CAS#:919-30-2

Literature: Toa Nenryo Kogyo Kabushiki Kaisha Patent: US4897501 A1, 1990 ;

1,5-cyclooctadiene

CAS#:1552-12-1

Triethoxysilane

CAS#:998-30-1

Allylamine

CAS#:107-11-9

~0%

beta-aminopropy...

CAS#:53218-21-6

Detail

Literature: Tonen Corporation Patent: EP284447 B1, 1991 ;

Triethoxysilane

CAS#:998-30-1

Allylamine

CAS#:107-11-9

~75%

3-Aminopropyltr...

CAS#:919-30-2

Literature: Toshiba Silicone Co., Ltd. Patent: US4649208 A1, 1987 ;

3-(triethoxysil...

CAS#:140236-87-9

3-Aminopropyltr...

CAS#:919-30-2

Literature: Chemical Communications, , # 1 p. 116 - 118

N-Allyl-1,1,1-t...

CAS#:10519-97-8

Triethoxysilane

CAS#:998-30-1

3-Aminopropyltr...

CAS#:919-30-2

Literature: Journal of Organic Chemistry, , vol. 24, p. 119

(2-cyanoethyl)t...

CAS#:919-31-3

3-Aminopropyltr...

CAS#:919-30-2

Literature: Mem.Fac.Eng.Osaka City Univ., , vol. 1, p. 1,6,11

Triethoxysilane

CAS#:998-30-1

Allylamine

CAS#:107-11-9

~69%

Tetraethyl orth...

CAS#:78-10-4

3-Aminopropyltr...

CAS#:919-30-2

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 53, # 7 p. 1591 - 1596,1435 - 1439

Triethoxysilane

CAS#:998-30-1

Allylamine

CAS#:107-11-9

~77%

3-Aminopropyltr...

CAS#:919-30-2

2-(Triethoxysil...

CAS#:36957-84-3

Literature: Chernyshev; Belyakova; Knyazeva; Pomerantseva; Efimova Russian Chemical Bulletin, 1998 , vol. 47, # 7 p. 1374 - 1378

Precursor 7
CAS#:5089-70-3 (3-Chloropropyl... CAS#:998-30-1 Triethoxysilane CAS#:107-11-9 Allylamine CAS#:1552-12-1 1,5-cyclooctadiene
CAS#:140236-87-9 3-(triethoxysil... CAS#:10519-97-8 N-Allyl-1,1,1-t... CAS#:919-31-3 (2-cyanoethyl)t...
DownStream 9
CAS#:106868-88-6 3-(4-semicarbaz... CAS#:106868-86-4 N-OCTADECYL-N'-... CAS#:105442-22-6 N',N'-dioctadec... CAS#:213818-61-2 3-(2,4-dihydro-...
CAS#:104-94-9 p-Anisidine CAS#:69952-89-2 1,3-Bis[3-(trie... CAS#:102-08-9 Thiocarbanilide CAS#:29275-19-2 N-(2-diethoxyph...
CAS#:1825-62-3 Ethoxy(trimethy...

HS Code	29310095

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Rice (N. Y.) 8 , 15, (2015)

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3-(triethoxysilyl)propan-1-amine

MFCD00025614

1-Propanamine, 3-(triethoxysilyl)-

(3-Aminopropyl)triethoxysilane

(γ-Aminopropyl)triethoxysilane

3-aminopropyl-triethoxysilane

3-aminopropyltriethoxy silane

APTES

1-Propanamine, 3- (triethoxysilyl)-

3-aminopropyl triethoxysilane

3-(Triethoxysilyl)-1-propanamine

Propylamine, 3- (triethoxysilyl)-

γ-aminopropyltriethoxysilane

γ-Aminopropyltriethoxy silane

3-Aminopropyltriethoxysilane

EINECS 213-048-4

Silane, (γ-aminopropyl)triethoxy-

3-aminopropyl(triethoxy)silane

Aminopropyltriethoxysilane

KH-550

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China
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China
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