OF 1

Modify Date: 2024-01-07 05:56:15

OF 1 Structure
OF 1 structure
Common Name OF 1
CAS Number 919973-83-4 Molecular Weight 440.311
Density 1.6±0.1 g/cm3 Boiling Point 573.8±60.0 °C at 760 mmHg
Molecular Formula C17H18BrN3O4S Melting Point N/A
MSDS Chinese USA Flash Point 300.8±32.9 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of OF 1


OF-1 is a selective BRPF1B and BRPF2 bromodomain inhibitor with Kd values of 100 nM/500 nM for BRPF1B/BRPF2; 39-fold selectivity over BRD4.

 Names

Name of-1
Synonym More Synonyms

 OF 1 Biological Activity

Description OF-1 is a selective BRPF1B and BRPF2 bromodomain inhibitor with Kd values of 100 nM/500 nM for BRPF1B/BRPF2; 39-fold selectivity over BRD4.
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 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 573.8±60.0 °C at 760 mmHg
Molecular Formula C17H18BrN3O4S
Molecular Weight 440.311
Flash Point 300.8±32.9 °C
Exact Mass 439.020142
PSA 90.71000
LogP 3.32
Appearance of Characters white to beige
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.644
Storage condition 2-8°C
Water Solubility DMSO: soluble5mg/mL, clear (warmed)

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H319
Precautionary Statements P301 + P310-P305 + P351 + P338
Hazard Codes T,Xi
Risk Phrases 25-36
Safety Phrases 26-45
RIDADR UN 2811 6.1 / PGIII

 Synonyms

4-Bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
Benzenesulfonamide, 4-bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-
4-​bromo-​N-​(2,​3-​dihydro-​6-​methoxy-​1,​3-​dimethyl-​2-​oxo-​1H-​benzimidazol-​5-​yl)-​2-​methyl-​benzenesulfonamide
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Price: $112/10mM*1mLinDMSO

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