Neuromedin N trifluoroacetate salt
Modify Date: 2024-01-02 18:53:28
Neuromedin N trifluoroacetate salt structure
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Common Name | Neuromedin N trifluoroacetate salt | ||
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| CAS Number | 92169-45-4 | Molecular Weight | 745.94900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H63N7O8 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Neuromedin N trifluoroacetate saltNeuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Sequence: Lys-Ile-Pro-Tyr-Ile-Leu. |
| Name | 2-[[2-[[2-[[1-[2-(2,6-diaminohexanoylamino)-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid |
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| Synonym | More Synonyms |
| Description | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Sequence: Lys-Ile-Pro-Tyr-Ile-Leu. |
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| Related Catalog | |
| Target |
Dopamine D2 receptor[1]. |
| In Vitro | Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin[2]. |
| References |
| Molecular Formula | C38H63N7O8 |
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| Molecular Weight | 745.94900 |
| Exact Mass | 745.47400 |
| PSA | 246.28000 |
| LogP | 4.44620 |
| Storage condition | -20°C |
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Detail
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| Literature: Kiso; Kimura; Fujiwara; Sakikawa; Akaji Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 1 p. 270 - 272 |
| Precursor 3 | |
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| DownStream 0 | |
| neuromedin N |
| Lys-ile-pro-tyr-ile-leu |