HG106

Modify Date: 2024-04-06 21:56:47

HG106 Structure
HG106 structure
Common Name HG106
CAS Number 928712-10-1 Molecular Weight 316.74
Density N/A Boiling Point N/A
Molecular Formula C15H13ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HG106


HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].

 Names

Name Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-

 HG106 Biological Activity

Description HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].
Related Catalog
References

[1]. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.  

 Chemical & Physical Properties

Molecular Formula C15H13ClN4O2
Molecular Weight 316.74