MK-1925

Modify Date: 2024-04-04 15:47:54

MK-1925 Structure
MK-1925 structure
Common Name MK-1925
CAS Number 932705-04-9 Molecular Weight 362.4
Density N/A Boiling Point N/A
Molecular Formula C19H21F3N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MK-1925


MK-1925 is a selective, orally active, brain-penetrant opioid receptor-like 1 (ORL1;NOP receptor) antagonist with binding IC50 of 8.2 nM; shows good selectivity over other opioid receptors and the hERG channel; exhibits in vivo antagonist activity against the reduction in locomotor activity induced by ORL1 agonist in mice.

 Names

Name MK-1925

 MK-1925 Biological Activity

Description MK-1925 is a selective, orally active, brain-penetrant opioid receptor-like 1 (ORL1;NOP receptor) antagonist with binding IC50 of 8.2 nM; shows good selectivity over other opioid receptors and the hERG channel; exhibits in vivo antagonist activity against the reduction in locomotor activity induced by ORL1 agonist in mice.
References References 1. Kobayashi K, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4729-32. View Related Products by Target Opioid Receptor

 Chemical & Physical Properties

Molecular Formula C19H21F3N4
Molecular Weight 362.4
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