MK-1925
Modify Date: 2024-04-04 15:47:54
MK-1925 structure
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Common Name | MK-1925 | ||
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| CAS Number | 932705-04-9 | Molecular Weight | 362.4 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H21F3N4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK-1925MK-1925 is a selective, orally active, brain-penetrant opioid receptor-like 1 (ORL1;NOP receptor) antagonist with binding IC50 of 8.2 nM; shows good selectivity over other opioid receptors and the hERG channel; exhibits in vivo antagonist activity against the reduction in locomotor activity induced by ORL1 agonist in mice. |
| Name | MK-1925 |
|---|
| Description | MK-1925 is a selective, orally active, brain-penetrant opioid receptor-like 1 (ORL1;NOP receptor) antagonist with binding IC50 of 8.2 nM; shows good selectivity over other opioid receptors and the hERG channel; exhibits in vivo antagonist activity against the reduction in locomotor activity induced by ORL1 agonist in mice. |
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| References | References 1. Kobayashi K, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4729-32. View Related Products by Target Opioid Receptor |
| Molecular Formula | C19H21F3N4 |
|---|---|
| Molecular Weight | 362.4 |