Nilofabicin

Modify Date: 2024-01-09 09:46:18

Nilofabicin Structure
Nilofabicin structure
Common Name Nilofabicin
CAS Number 934628-27-0 Molecular Weight 340.44
Density 1.273 g/cm3 Boiling Point 607.121ºC at 760 mmHg
Molecular Formula C19H20N2O2S Melting Point N/A
MSDS N/A Flash Point 320.975ºC

 Use of Nilofabicin


Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].

 Names

Name 1-[(3-amino-2-methylphenyl)methyl]-4-(2-thiophen-2-ylethoxy)pyridin-2-one
Synonym More Synonyms

 Nilofabicin Biological Activity

Description Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].
Related Catalog
References

[1]. Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591–2593.

 Chemical & Physical Properties

Density 1.273 g/cm3
Boiling Point 607.121ºC at 760 mmHg
Molecular Formula C19H20N2O2S
Molecular Weight 340.44
Flash Point 320.975ºC
Exact Mass 340.12500
PSA 85.49000
LogP 4.05140
Storage condition -20°C

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

unii-4x6t64d64x
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