Compound 48/80
Modify Date: 2024-01-02 10:52:12
Compound 48/80 structure
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Common Name | Compound 48/80 | ||
|---|---|---|---|---|
| CAS Number | 94724-12-6 | Molecular Weight | 519.72 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H45N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Compound 48/80Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2]. |
| Name | hydrogen, 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylam ino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]ph enyl]-N-methyl-ethanamine, dihydrochloride |
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| Synonym | More Synonyms |
| Description | Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2]. |
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| Related Catalog | |
| Target |
Mast Cell Activator[1] |
| In Vitro | Compound 48/80 (poly-p-methoxyphenethylmethylamine), an agent commonly used to trigger degranulation of mast cells, at concentrations of 5-20 μg/ml suppresses the proliferation of L1210 and Friend leukemic cells in vitro, inducing the formation of giant cells, which are polykaryons[3]. |
| References |
| Molecular Formula | C32H45N3O3 |
|---|---|
| Molecular Weight | 519.72 |
| Exact Mass | 597.34600 |
| PSA | 63.78000 |
| LogP | 6.95640 |
| Hazard Codes | T: Toxic; |
|---|---|
| Risk Phrases | 23/24/25 |
| Safety Phrases | 22-24/25-45-36/37 |
| RIDADR | UN 2811 6.1/PG 2 |
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Compound 48/80 CAS#:94724-12-6 |
| Literature: IMPERIAL COLLEGE INNOVATIONS LTD Patent: WO2005/23744 A2, 2005 ; Location in patent: Page/Page column 16; 20-21 ; |
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~%
Compound 48/80 CAS#:94724-12-6 |
| Literature: Katsu; Ono; Tasaka; Fujita Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4185 - 4188 |
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~%
Compound 48/80 CAS#:94724-12-6 |
| Literature: Katsu; Ono; Tasaka; Fujita Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 4185 - 4188 |
![1-(2-chloroethyl)-4-methoxy-3,5-{bis[2-methoxy-5-(2-chloroethyl)phenyl]methane}benzene structure](https://image.chemsrc.com/caspic/213/848035-20-1.png)
| Benzenediazonium,2-carboxy-,chloride |
| MFCD00077679 |
| compound 48/80 |
| benzenediazonium 2-carboxylate hydrochloride |
| 2-Carboxy-benzoldiazonium,Chlorid |
| o-carboxybenzenediazonium chloride |
| 2-carboxy-benzenediazonium chloride |
| benzeneethanamine-4-methoxy-3,5-bis{(2-methoxy-5-(2-methylaminoethyl)phenyl)methyl-N-methyl} |