LJP 1586

Modify Date: 2024-01-08 07:20:29

LJP 1586 Structure
LJP 1586 structure
Common Name LJP 1586
CAS Number 955037-42-0 Molecular Weight 231.69
Density N/A Boiling Point N/A
Molecular Formula C11H15ClFNO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LJP 1586


LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].

 Names

Name (2Z)-3-Fluoro-2-(4-methoxybenzyl)-2-propen-1-amine hydrochloride (1:1)
Synonym More Synonyms

 LJP 1586 Biological Activity

Description LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].
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References

[1]. O'Rourke AM, et al. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J Pharmacol Exp Ther. 2008 Feb;324(2):867-75.  

 Chemical & Physical Properties

Molecular Formula C11H15ClFNO
Molecular Weight 231.69
Exact Mass 231.082626

 Synonyms

(2Z)-3-Fluoro-2-(4-methoxybenzyl)-2-propen-1-amine hydrochloride (1:1)
Benzenepropanamine, β-(fluoromethylene)-4-methoxy-, (βZ)-, hydrochloride (1:1)
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