DPA-714 structure
|
Common Name | DPA-714 | ||
---|---|---|---|---|
CAS Number | 958233-07-3 | Molecular Weight | 398.474 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C22H27FN4O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of DPA-714DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model[1][2]. |
Name | DPA-714 |
---|---|
Synonym | More Synonyms |
Description | DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model[1][2]. |
---|---|
Related Catalog | |
Target |
Ki: 7 nM (TSPO)[1] |
References |
Density | 1.2±0.1 g/cm3 |
---|---|
Molecular Formula | C22H27FN4O2 |
Molecular Weight | 398.474 |
Exact Mass | 398.211792 |
LogP | 2.86 |
Index of Refraction | 1.581 |
Pyrazolo[1,5-a]pyrimidine-3-acetamide, N,N-diethyl-2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethyl- |
DPA-714 |
N,N-Diethyl-2-{2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl}acetamide |
Y1H4D2VKZD |