Ecomustine

Modify Date: 2024-01-03 12:08:16

Ecomustine structure	Common Name	Ecomustine
	CAS Number	98383-18-7	Molecular Weight	311.72
	Density	1.59g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₈ClN₃O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ecomustine

Ecomustine (CY233) is a nitrosoureido sugar derived from acosamine. Ecomustine shows antitumour activity[1].

Name	Ecomustine
Synonym	More Synonyms

Description	Ecomustine (CY233) is a nitrosoureido sugar derived from acosamine. Ecomustine shows antitumour activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. el Abed I, et al. Chemical stability of ecomustine, a new antitumor agent in aqueous and biological media as assessed by high-performance liquid chromatography. Cancer Chemother Pharmacol. 1991;27(4):295-300.

Density	1.59g/cm3
Molecular Formula	C₁₀H₁₈ClN₃O₆
Molecular Weight	311.72
Exact Mass	311.08800
PSA	120.69000
Index of Refraction	1.597

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MQ3130200

CHEMICAL NAME :: alpha-D-arabino-Hexopyranoside, methyl 3-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-2,3- dideoxy-

CAS REGISTRY NUMBER :: 98383-18-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H18-Cl-N3-O6

MOLECULAR WEIGHT :: 311.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,16,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,16,1989

a-D-arabino-Hex...

CAS#:6386-19-2

Ecomustine

CAS#:98383-18-7

Literature: Roger; Monneret; Fournier; Choay; Gagnet; Gosse; Letourneux; Atassi; Gouyette Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 16 - 23

N/A

CAS#:20379-53-7

Ecomustine

CAS#:98383-18-7

Literature: Roger; Monneret; Fournier; Choay; Gagnet; Gosse; Letourneux; Atassi; Gouyette Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 16 - 23

1-(2-chloroethy...

CAS#:98383-19-8

Ecomustine

CAS#:98383-18-7

Literature: Roger; Monneret; Fournier; Choay; Gagnet; Gosse; Letourneux; Atassi; Gouyette Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 16 - 23

methyl 3-amino-...

CAS#:16697-56-6

Ecomustine

CAS#:98383-18-7

Literature: Roger; Monneret; Fournier; Choay; Gagnet; Gosse; Letourneux; Atassi; Gouyette Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 16 - 23

Precursor 2
CAS#:6386-19-2 a-D-arabino-Hex... CAS#:16697-56-6 methyl 3-amino-...
DownStream 0

cy-233

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Ecomustine

Use of Ecomustine

Names

Ecomustine Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms