Ecomustine

Modify Date: 2024-01-03 12:08:16

Ecomustine Structure
Ecomustine structure
 Common Name Ecomustine
CAS Number 98383-18-7 Molecular Weight 311.72
Density 1.59g/cm3 Boiling Point N/A
Molecular Formula C10H18ClN3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ecomustine


Ecomustine (CY233) is a nitrosoureido sugar derived from acosamine. Ecomustine shows antitumour activity[1].

 Names

Name Ecomustine
Synonym More Synonyms

 Ecomustine Biological Activity

Description Ecomustine (CY233) is a nitrosoureido sugar derived from acosamine. Ecomustine shows antitumour activity[1].
Related Catalog
References

[1]. el Abed I, et al. Chemical stability of ecomustine, a new antitumor agent in aqueous and biological media as assessed by high-performance liquid chromatography. Cancer Chemother Pharmacol. 1991;27(4):295-300.  

 Chemical & Physical Properties

Density 1.59g/cm3
Molecular Formula C10H18ClN3O6
Molecular Weight 311.72
Exact Mass 311.08800
PSA 120.69000
Index of Refraction 1.597

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MQ3130200
CHEMICAL NAME :
alpha-D-arabino-Hexopyranoside, methyl 3-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-2,3- dideoxy-
CAS REGISTRY NUMBER :
98383-18-7
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H18-Cl-N3-O6
MOLECULAR WEIGHT :
311.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,16,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,16,1989

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

cy-233
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