SQ-29548

Modify Date: 2024-01-04 10:27:52

Use of SQ-29548

SQ 29548, a high affinity radioligand, is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].

Name	[3h]-sq 29548
Synonym	More Synonyms

Description	SQ 29548, a high affinity radioligand, is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Metabolic Disease
References	[1]. Isabella Lawandy, et al. Increased coronary arteriolar contraction to serotonin in juvenile pigs with metabolic syndrome. Mol Cell Biochem. 2019 Nov;461(1-2):57-64. [2]. A Hedberg, et al. Characterization of [5, 6-3H] SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets. J Pharmacol Exp Ther. 1988 Jun;245(3):786-92.

Description

SQ 29548, a high affinity radioligand, is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

Research Areas >> Metabolic Disease

References

methyl [1S-[1α,...

CAS#:128781-28-2

SQ-29548

CAS#:98672-91-4

Literature: Nakane, Masami; Reid, Joyce A.; Han, Wen-Ching; Das, Jagabandhu; Truc, Vu Chi; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2465 - 2476

Precursor 1
CAS#:128781-28-2 methyl [1S-[1α,...
DownStream 0

(5Z)-7-[(1R,2R,3R,4S)-3-{[2-(Phenylcarbamoyl)hydrazino]methyl}-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid

5-Heptenoic acid, 7-((1R,2R,3R,4S)-3-((2-((phenylamino)carbonyl)hydrazino)methyl)-7-oxabicyclo(2.2.1)hept-2-yl)-, (5Z)-rel-

5-Heptenoic acid, 7-[(1R,2R,3R,4S)-3-[[2-[(phenylamino)carbonyl]hydrazinyl]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-, (5Z)-