iofendylate

Modify Date: 2024-02-02 18:27:09

iofendylate Structure
iofendylate structure
Common Name iofendylate
CAS Number 99-79-6 Molecular Weight 416.33700
Density 1.261g/cm3 Boiling Point 421.2ºC at 760mmHg
Molecular Formula C19H29IO2 Melting Point 25°C
MSDS N/A Flash Point 208.5ºC

 Use of iofendylate


Iophendylate (Pantopaque) is a highly lipophilic substance, and can be used as a contrast medium. Iophendylate is mainly for brain and spinal cord visualization[1][2].

 Names

Name Ethyl 10-(4-iodophenyl)undecanoate
Synonym More Synonyms

 iofendylate Biological Activity

Description Iophendylate (Pantopaque) is a highly lipophilic substance, and can be used as a contrast medium. Iophendylate is mainly for brain and spinal cord visualization[1][2].
Related Catalog

 Chemical & Physical Properties

Density 1.261g/cm3
Boiling Point 421.2ºC at 760mmHg
Melting Point 25°C
Molecular Formula C19H29IO2
Molecular Weight 416.33700
Flash Point 208.5ºC
Exact Mass 416.12100
PSA 26.30000
LogP 6.07860
Index of Refraction 1.526

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ2550000
CHEMICAL NAME :
Undecanoic acid, 10-(p-iodophenyl)-, ethyl ester
CAS REGISTRY NUMBER :
99-79-6
BEILSTEIN REFERENCE NO. :
2661373
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C19-H29-I-O2
MOLECULAR WEIGHT :
416.38
WISWESSER LINE NOTATION :
IR DY1&8VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,65,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RADLAX Radiology. (Radiological Soc. of North America, 20th & Northampton Sts., Easton, PA 18042) V.1- 1923- Volume(issue)/page/year: 43,230,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4722 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 702 (estimated) No. of Female Employees: 359 (estimated)

 Safety Information

HS Code 2916399090

 Synthetic Route

~%

iofendylate Structure

iofendylate

CAS#:99-79-6

Literature: Journal of the American Chemical Society, , vol. 64, p. 1436,1438

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

Iophendylate,p
10-(4-Jod-phenyl)-undecansaeure-aethylester
Aethyl-9-(p-Iodphenyl)-9-methyl-decanoat
Ethiodan
Iofendylate
Mulsopaque
Neurotrast
IOPHENDYLATE
10-(4-iodo-phenyl)-undecanoic acid ethyl ester
Jofendylatum
Myodil
Myodyl