(R)-NADH-d1

Modify Date: 2024-08-05 09:37:39

(R)-NADH-d1 Structure
(R)-NADH-d1 structure
Common Name (R)-NADH-d1
CAS Number 10012-96-1 Molecular Weight 666.44700
Density N/A Boiling Point N/A
Molecular Formula C21H28DN7O14P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-NADH-d1


(R)-NADH-d1 is the deuterium labeled (R)-NADH. NADH is an orally active reduced coenzyme. NADH is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle[1][2].

 Names

Name [4r-(2h)]nadh
Synonym More Synonyms

 (R)-NADH-d1 Biological Activity

Description (R)-NADH-d1 is the deuterium labeled (R)-NADH. NADH is an orally active reduced coenzyme. NADH is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

 Chemical & Physical Properties

Molecular Formula C21H28DN7O14P2
Molecular Weight 666.44700
Exact Mass 666.13100
PSA 337.24000

 Synonyms

(4R)-[4-2H]-NADH
4R-D-NADH
O5'-{2-[1-(3-carbamoyl-4H-pyridin-1-yl)-β-D-1-deoxy-ribofuranos-5-yloxy]-1,2-dihydroxy-phosphoryl}-adenosine
diphosphoric acid-1-adenosin-5'-yl ester-2-[(1R)-1-((4R)-3-carbamoyl-4-deuterio-4H-[1]pyridyl)-D-1,4-anhydro-ribitol-5-yl ester]
Diphosphorsaeure-1-adenosin-5'-ylester-2-[(1R)-1-((4R)-3-carbamoyl-4-deuterio-4H-[1]pyridyl)-D-1,4-anhydro-ribit-5-ylester]
[4R-2H]-NADH