Valnoctamide-d5

Modify Date: 2024-01-19 16:58:33

Valnoctamide-d5 structure	Common Name	Valnoctamide-d5
	CAS Number	1190015-82-7	Molecular Weight	148.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈H₁₂D₅NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Valnoctamide-d5

Valnoctamide-d5 (Valmethamide-d5) is the deuterium labeled Valnoctamide. Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors[1][2].

Name	Valnoctamide-d5

Description	Valnoctamide-d5 (Valmethamide-d5) is the deuterium labeled Valnoctamide. Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Spampanato J, et al. Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus. Epilepsia. 2014 Sep;55(9):e94-8.

Molecular Formula	C₈H₁₂D₅NO
Molecular Weight	148.26

Valnoctamide-d5

Use of Valnoctamide-d5

Names

Valnoctamide-d5 Biological Activity

Chemical & Physical Properties