Dabigatran-13C6
Modify Date: 2024-04-06 13:24:08
Dabigatran-13C6 structure
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Common Name | Dabigatran-13C6 | ||
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| CAS Number | 1210608-88-0 | Molecular Weight | 477.46700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H25N7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Dabigatran-13C6Dabigatran-13C6 is the 13C labeled Dabigatran[1]. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM)[2][3]. |
| Name | 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid |
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| Synonym | More Synonyms |
| Description | Dabigatran-13C6 is the 13C labeled Dabigatran[1]. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM)[2][3]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C25H25N7O3 |
|---|---|
| Molecular Weight | 477.46700 |
| Exact Mass | 477.22200 |
| PSA | 150.22000 |
| LogP | 3.85900 |
| bibr 953zw |