Desmethylsildenafil-d8 citrate

Modify Date: 2024-01-02 19:26:16

Desmethylsildenafil-d8 citrate Structure
Desmethylsildenafil-d8 citrate structure
Common Name Desmethylsildenafil-d8 citrate
CAS Number 1215071-06-9 Molecular Weight 660.72300
Density N/A Boiling Point N/A
Molecular Formula C27H28D8N6O11S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Desmethylsildenafil-d8 citrate


Desmethylsildenafil-d8 (citrate) is the deuterium labeled Desmethylsildenafil citrate[1].

 Names

Name 5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one,2-hydroxypropane-1,2,3-tricarboxylic acid
Synonym More Synonyms

 Desmethylsildenafil-d8 citrate Biological Activity

Description Desmethylsildenafil-d8 (citrate) is the deuterium labeled Desmethylsildenafil citrate[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C27H28D8N6O11S
Molecular Weight 660.72300
Exact Mass 660.26600
PSA 262.72000
LogP 1.36770

 Synonyms

[2H8]-N-Desmethyl Sildenafil citrate
Desmethylsildenafil-d8 Citrate