PD 132002

Modify Date: 2024-01-02 11:04:58

PD 132002 structure	Common Name	PD 132002
	CAS Number	134452-04-3	Molecular Weight	654.81500
	Density	1.28g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₁H₅₀N₄O₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PD 132002

PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure[1].

Name	methyl (2R)-2-[[(2S,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]-3-oxopropanoate
Synonym	More Synonyms

Description	PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Renin
References	[1]. J T Repine, et al. Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate. J Med Chem. 1991 Jul;34(7):1935-43.

Density	1.28g/cm3
Molecular Formula	C₃₁H₅₀N₄O₉S
Molecular Weight	654.81500
Exact Mass	654.33000
PSA	195.47000
LogP	3.28600
Index of Refraction	1.579

methyl <1S-(1R*,2S*,3R*)>-3-<<1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl>amino>-N-<N-(4-morpholinylsulfonyl)-L-phenylalanyl>-3-oxo-DL-alaninate

(1S-(1R*,2S*,3R*))-3-{[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]amino}-N-[N-(4-morpholinosulfonyl)-L-phenylalanyl]-3-oxo-DL-alanine methyl ester

2-methoxy-6-[(4-methylphenyl)sulfonyloxymethyl]oxane-3,4,5-triol

PD 132002

Use of PD 132002

Names

PD 132002 Biological Activity

Chemical & Physical Properties

Synonyms