mGlu4 receptor agonist 1

Modify Date: 2024-01-08 01:14:38

mGlu4 receptor agonist 1 Structure
mGlu4 receptor agonist 1 structure
Common Name mGlu4 receptor agonist 1
CAS Number 1678501-16-0 Molecular Weight 390.82
Density N/A Boiling Point N/A
Molecular Formula C21H15ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mGlu4 receptor agonist 1


mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].

 Names

Name mGlu4 receptor agonist 1

 mGlu4 receptor agonist 1 Biological Activity

Description mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].
Related Catalog
Target

mGluR4:308 ± 35 nM (EC50)

References

[1]. Stankiewicz A, et al. New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties. J Enzyme Inhib Med Chem. 2022 Dec;37(1):211-225.

 Chemical & Physical Properties

Molecular Formula C21H15ClN4O2
Molecular Weight 390.82