Suberic acid-d12

Modify Date: 2024-01-06 17:58:29

Suberic acid-d12 structure	Common Name	Suberic acid-d12
	CAS Number	169397-99-3	Molecular Weight	186.26800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈H₂D₁₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Suberic acid-d12

Suberic acid-d12 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].

Name	1,8-octanedioic-d12 acid

Description	Suberic acid-d12 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Gregersen N, et al. General (medium-chain) acyl-CoA dehydrogenase deficiency (non-ketotic dicarboxylic aciduria): quantitative urinary excretion pattern of 23 biologically significant organic acids in three cases. Clin Chim Acta. 1983 Aug 15;132(2):181-91.

Molecular Formula	C₈H₂D₁₂O₄
Molecular Weight	186.26800
Exact Mass	186.16500
PSA	74.60000
LogP	1.49620