A2AAR antagonist 1

Modify Date: 2024-09-17 07:47:22

A2AAR antagonist 1 Structure
A2AAR antagonist 1 structure
Common Name A2AAR antagonist 1
CAS Number 1784491-64-0 Molecular Weight 290.12
Density N/A Boiling Point N/A
Molecular Formula C12H8BrN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A2AAR antagonist 1


A2AAR antagonist 1 (compound 21a) is an A2AAR (adenosine A2A receptor) antagonist with a Ki value of 20 nM. A2AAR antagonist 1 shows high ligand efficiency, and it can be used for the research of neurodegenerative diseases[1].

 Names

Name A2AAR antagonist 1

 A2AAR antagonist 1 Biological Activity

Description A2AAR antagonist 1 (compound 21a) is an A2AAR (adenosine A2A receptor) antagonist with a Ki value of 20 nM. A2AAR antagonist 1 shows high ligand efficiency, and it can be used for the research of neurodegenerative diseases[1].
Related Catalog
In Vitro A2AAR antagonist 1 (0-10 μM; 1 h) shows a high affinity towards A2AAR with a Ki value of 20 nM[1].
References

[1]. Bolteau R, et al. High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists. Eur J Med Chem. 2022 Nov 5;241:114620.

 Chemical & Physical Properties

Molecular Formula C12H8BrN3O
Molecular Weight 290.12