A2AAR antagonist 1

Modify Date: 2024-09-17 07:47:22

A2AAR antagonist 1 structure	Common Name	A2AAR antagonist 1
	CAS Number	1784491-64-0	Molecular Weight	290.12
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₈BrN₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of A2AAR antagonist 1

A2AAR antagonist 1 (compound 21a) is an A2AAR (adenosine A2A receptor) antagonist with a Ki value of 20 nM. A2AAR antagonist 1 shows high ligand efficiency, and it can be used for the research of neurodegenerative diseases[1].

Name	A2AAR antagonist 1

Description	A2AAR antagonist 1 (compound 21a) is an A2AAR (adenosine A2A receptor) antagonist with a Ki value of 20 nM. A2AAR antagonist 1 shows high ligand efficiency, and it can be used for the research of neurodegenerative diseases[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	A2AAR antagonist 1 (0-10 μM; 1 h) shows a high affinity towards A2AAR with a Ki value of 20 nM[1].
References	[1]. Bolteau R, et al. High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists. Eur J Med Chem. 2022 Nov 5;241:114620.

Molecular Formula	C₁₂H₈BrN₃O
Molecular Weight	290.12

A2AAR antagonist 1

Use of A2AAR antagonist 1

Names

A2AAR antagonist 1 Biological Activity

Chemical & Physical Properties