5a-Androstane-3a,17b-diol

Modify Date: 2024-01-02 06:41:42

5a-Androstane-3a,17b-diol Structure
5a-Androstane-3a,17b-diol structure
Common Name 5a-Androstane-3a,17b-diol
CAS Number 1852-53-5 Molecular Weight 292.45600
Density 1.09g/cm3 Boiling Point 415ºC at 760 mmHg
Molecular Formula C19H32O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Names

Name 5α-androstane-3α,17β-diol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.09g/cm3
Boiling Point 415ºC at 760 mmHg
Molecular Formula C19H32O2
Molecular Weight 292.45600
Exact Mass 292.24000
PSA 40.46000
LogP 3.75090
Vapour Pressure 1.27E-08mmHg at 25°C
Index of Refraction 1.546

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8044310
CHEMICAL NAME :
5-alpha-Androstane-3-alpha,17-beta-diol
CAS REGISTRY NUMBER :
1852-53-5
BEILSTEIN REFERENCE NO. :
2694353
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H32-O2
MOLECULAR WEIGHT :
292.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
48 mg/kg
SEX/DURATION :
male 6 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
JSTBBK Journal of Steroid Biochemistry. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 0BW, UK) V.1- 1969- Volume(issue)/page/year: 18,397,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
8 mg/kg
SEX/DURATION :
female 13-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 99,1490,1976
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
40 mg/kg
SEX/DURATION :
female 13-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - skin and skin appendages
REFERENCE :
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 99,1490,1976
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
200 ug/kg
SEX/DURATION :
male 20 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 89,69,1990

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS BV8044310

 Synthetic Route

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 Synonyms

5a-androstane-3a,17b-diol
5A-ANDROSTAN-3A,17SS-DIOL
5alpha-androstane-3alpha,17beta-diol
dihydroandrosterone
DIHYDROANDROSTANEDIOL
[3H]-Hombreol
Hombreol
Etiocholane-3alpha,17beta-diol
EINECS 217-447-4
Androstane-3alpha,17beta-diol
5-ANDROSTANEDIOL
5.α.-Androstane-3.α.,17.β.-androstanediol
5A-ANDROSTAN-3A,17B-DIOL
MFCD00003676