BuChE-IN-6

Modify Date: 2024-01-29 17:19:38

BuChE-IN-6 structure	Common Name	BuChE-IN-6
	CAS Number	2003213-07-6	Molecular Weight	366.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₆N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BuChE-IN-6

BuChE-IN-6 (compound 1b) is a potent and selective BuChE (butyrylcholinesterase) inhibitor, with IC50 values of 0.46 and 0.51 μM for eqBuChE and hBuChE, respectively. BuChE-IN-6 also inhibits Aβ42 self-aggregation[1].

Name	BuChE-IN-6

Description	BuChE-IN-6 (compound 1b) is a potent and selective BuChE (butyrylcholinesterase) inhibitor, with IC50 values of 0.46 and 0.51 μM for eqBuChE and hBuChE, respectively. BuChE-IN-6 also inhibits Aβ42 self-aggregation[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	Butyrylcholinesterase:0.46 μM (IC50, eqBuChE) Butyrylcholinesterase:0.51 μM (IC50, hBuChE)
References	[1]. Marques CS, et al. N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study. Bioorg Chem. 2020 May;98:103753.

Molecular Formula	C₂₁H₂₆N₄O₂
Molecular Weight	366.46